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職稱：副研究員

學(xué)歷：博士

電話：0591-22866373

電子郵件： ypxie@fzu.edu.cn

研究方向：微藻生物技術(shù)、生物發(fā)酵與代謝調(diào)控、生物物質(zhì)分離純化

教育工作經(jīng)歷：

2019.09-至今：福州海洋研究院海洋生物制造技術(shù)研發(fā)中心，常務(wù)副主任

2017.12-至今：海洋生物高值高質(zhì)化利用技術(shù)創(chuàng)新服務(wù)平臺(tái)，常務(wù)副主任

2017.03-至今：福建省海產(chǎn)品廢棄物綜合利用工程技術(shù)研究中心，常務(wù)副主任

2015.08-至今：福州市海產(chǎn)品高值化利用行業(yè)技術(shù)創(chuàng)新中心，常務(wù)副主任

2014.08-至今：beat365在線體育官網(wǎng)beat365在線體育官網(wǎng)，助理研究員、副研究員

2012.09-2013.02：臺(tái)灣成功大學(xué)張嘉修（Jo-Shu Chang）教授實(shí)驗(yàn)室，訪學(xué)

2004.09-2014.07：廈門大學(xué)，化學(xué)化工學(xué)院，工學(xué)學(xué)士、工學(xué)碩士、工學(xué)博士

教學(xué)簡介：

主講本科生課程《生物分離工程》，碩士研究生課程《綠色生物制造》、《生物資源開發(fā)利用》。指導(dǎo)研究生多次獲得國家獎(jiǎng)學(xué)金、福建省優(yōu)秀學(xué)位論文、beat365在線體育官網(wǎng)優(yōu)秀學(xué)位論文、beat365在線體育官網(wǎng)研究生高水平學(xué)術(shù)成果獎(jiǎng)等。

科研簡介：

主要從事微藻生物技術(shù)、生物發(fā)酵與代謝調(diào)控、生物物質(zhì)分離純化等領(lǐng)域的研究工作。已先后主持國家“十三五”海洋經(jīng)濟(jì)創(chuàng)新發(fā)展示范項(xiàng)目子課題、國家自然科學(xué)基金項(xiàng)目、福建省自然科學(xué)基金項(xiàng)目、福州市市校（院所）科技合作項(xiàng)目和福州海洋研究院科技項(xiàng)目等10余項(xiàng)，并作為技術(shù)負(fù)責(zé)人參與福建省海洋高新產(chǎn)業(yè)發(fā)展專項(xiàng)、福建省科技廳高校產(chǎn)學(xué)合作重大項(xiàng)目、福州市省級(jí)海洋經(jīng)濟(jì)發(fā)展補(bǔ)助資金項(xiàng)目等10余項(xiàng)。以第一作者/通訊作者身份在Bioresour. Technol., Chem. Eng. J., Biotechnol. Biof. Biop., Algal Res., Mar. Drugs, Biotechnol. J., Biochem. Eng. J.等期刊上發(fā)表學(xué)術(shù)論文30余篇（中科院JCR大類學(xué)科1區(qū)Top期刊11篇，2區(qū)期刊12篇），作為共同作者發(fā)表學(xué)術(shù)論文30余篇，論文總被引1300余次（WOS），H指數(shù)24（WOS）。申請(qǐng)發(fā)明專利22件，已授權(quán)發(fā)明專利10件。獲福建省科學(xué)技術(shù)進(jìn)步獎(jiǎng)三等獎(jiǎng)1項(xiàng)。2021年入選福建省級(jí)高層次人才C類。

社會(huì)兼職：

民盟福建省生態(tài)環(huán)境委員會(huì)委員；民盟beat365在線體育官網(wǎng)委員會(huì)組織委員；福建省科技特派員；福州市科技特派員；擔(dān)任Bioresour. Technol., Chem. Eng. J., Env. Sci. Ecotechnol., J. Hazard. Mater., J. Clean. Prod., Biotechnol. Biofuels, Algal Res., J. Taiwan Inst. Chem. E., Front. Microbiol., Front. Bioeng. Biotech., Biochem. Eng. J., Process Biochem., Int. J. Hydrogen Energ.等多本SCI期刊審稿人。

主要科研項(xiàng)目：

（1）國家“十三五”海洋經(jīng)濟(jì)創(chuàng)新發(fā)展示范項(xiàng)目，海洋生物高值高質(zhì)化利用技術(shù)創(chuàng)新服務(wù)平臺(tái)，2016-2019，子平臺(tái)負(fù)責(zé)人。

（2）國家“十三五”海洋經(jīng)濟(jì)創(chuàng)新發(fā)展示范項(xiàng)目，海洋微藻高值化產(chǎn)品開發(fā)及產(chǎn)業(yè)鏈建設(shè)，2017-2019，子課題負(fù)責(zé)人。

（3）國家“十三五”海洋經(jīng)濟(jì)創(chuàng)新發(fā)展示范項(xiàng)目，魷魚內(nèi)臟高值化產(chǎn)品開發(fā)及年產(chǎn)350噸海洋農(nóng)用制品生產(chǎn)線建設(shè)，2017-2019，子課題負(fù)責(zé)人。

（4）國家自然科學(xué)基金應(yīng)急管理項(xiàng)目，海洋衣藻自養(yǎng)積累葉黃素的調(diào)控機(jī)制研究， 2017-2017，主持。

（5）福建省海洋高新產(chǎn)業(yè)發(fā)展專項(xiàng)項(xiàng)目，海洋微藻開發(fā)利用與水產(chǎn)養(yǎng)殖廢水凈化的耦合處理關(guān)鍵技術(shù)研發(fā)，2016-2018，技術(shù)負(fù)責(zé)人。

（6）2019年福州市省級(jí)海洋經(jīng)濟(jì)發(fā)展補(bǔ)助資金項(xiàng)目，低值海魚綜合利用關(guān)鍵技術(shù)研發(fā)及產(chǎn)業(yè)化，2019-2020，技術(shù)負(fù)責(zé)人。

（7）2022年度福州海洋研究院科技項(xiàng)目，海洋小球藻高密度異養(yǎng)聯(lián)產(chǎn)蛋白質(zhì)和葉黃素的關(guān)鍵技術(shù)開發(fā)及中試熟化，2022-2024，主持。

代表性論文：（*為通訊作者）

(1) Ruijuan Ma#, Zhen Zhang#, Hong Fang, Xinyu Liu, Shih-Hsin Ho, Youping Xie*, Jianfeng Chen*. Unveiling the underlying molecular mechanisms of high lutein production efficiency in Chlorella sorokiniana FZU60 under a mixotrophy/photoautotrophy two-stage strategy by transcriptomic, physiological, and biochemical analyses. Biotechnology for Biofuels and Bioproducts, 2023, 16: 47.

(2) Hong Fang, Junjie Liu, Ruijuan Ma*, Yiping Zou, Shih-Hsin Ho, Jianfeng Chen, Youping Xie*. Functional characterization of lycopene b- and e-cyclases from a lutein-enriched green microalga Chlorella sorokiniana FZU60. Marine Drugs, 2023, 21: 418.

(3) Ruijuan Ma#, Yuanwei You#, Xinyu Liu, Shih-Hsin Ho, Youping Xie*, Jianfeng Chen*. Highly efficient co-production of fucoxanthin and eicosapentaenoic acid by heterotrophic cultivation of a newly isolated microalga Nitzschia sp. FZU62. Algal Research, 2023, 71: 103046.

(4) Youping Xie^#, Zhen Zhang^#, Ruijuan Ma^#, Xinyu Liu, Miao Miao, Shih-Hsin Ho, Jianfeng Chen, Yoong Kit Leonge, Jo-Shu Chang*. High-cell-density heterotrophic cultivation of microalga Chlorella sorokiniana FZU60 for achieving ultra-high lutein production efficiency. Bioresource Technology, 2022, 365: 128130.

(5) Hongling Ke^#, Ruijuan Ma^#, Xinyu Liu, Youping Xie*, Jianfeng Chen*. Highly effective peptide-calcium chelate prepared from aquatic products processing wastes: stickwater and oyster shells. LWT-Food Science and Technology, 2022, 168: 113947.

(6) Youping Xie, Kuan Shiong Khoo, Kit Wayne Chew, Vishno Vardhan Devadas, Sue Jiun Phang, Hooi Ren Lim, Saravanan Rajendran, Pau Loke Show*. Advancement of renewable energy technologies via artificial and microalgae photosynthesis. Bioresource Technology, 2022, 363: 127830.

(7) Ruijuan Ma^#, Xinyi Tao^#, Elvis T. Chua^#, Shih-Hsin Ho, Xinguo Shi, Lemian Liu, Youping Xie*, Jianfeng Chen. Enhancing astaxanthin production in Haematococcus pluvialis QLD by a pH steady NaHCO₃-CO₂-C/NH₄Cl-N culture system. Algal Research, 2022, 64: 102697.

(8) Ruijuan Ma^#, Zhen Zhang^#, Zhuzhen Tang, Shih-Hsin Ho, Xinguo Shi, Lemian Liu, Youping Xie*, Jianfeng Chen. Enhancement of co-production of lutein and protein in Chlorella sorokiniana FZU60 using different bioprocess operation strategies. Bioresources and Bioprocessing, 2021, 8: 82.

(9) Ruijuan Ma, Zhen Zhang, Shih-Hsin Ho, Chengxu Ruan, Jun Li, Youping Xie*, Xinguo Shi, Lemian Liu, Jianfeng Chen*. Two-stage bioprocess for hyper-production of lutein from microalga Chlorella sorokiniana FZU60: Effects of temperature, light intensity, and operation strategies. Algal Research, 2020, 52: 102119.

(10) Ruijuan Ma^#, Baobei Wang^#, Elvis T. Chua^#, Xurui Zhao, Kongyong Lu, Shih-Hsin Ho, Xinguo Shi, Lemian Liu, Youping Xie*, Yinghua Lu, Jianfeng Chen*. Comprehensive utilization of marine microalgae for enhanced co-production of multiple compounds. Marine Drugs, 2020, 18: 467.

(11) Youping Xie, Jun Li, Shih-Hsin Ho, Ruijuan Ma*, Xinguo Shi, Lemian Liu, Jianfeng Chen. Pilot-scale cultivation of Chlorella sorokiniana FZU60 with a mixotrophy/photoautotrophy two-stage strategy for efficient lutein production. Bioresource Technology, 2020, 314: 123767.

(12) Ruijuan Ma, Xurui Zhao, Shih-Hsin Ho, Xinguo Shi, Lemian Liu, Youping Xie*, Jianfeng Chen*, Yinghua Lu. Co-production of lutein and fatty acid in microalga Chlamydomonas sp. JSC4 in response to different temperatures with gene expression profiles. Algal Research, 2020, 47: 101821.

(13) Youping Xie, Jun Li, Ruijuan Ma, Shih-Hsin Ho, Xinguo Shi, Lemian Liu, Jianfeng Chen*. Bioprocess operation strategies with mixotrophy/photoinduction to enhance lutein production of microalga Chlorella sorokiniana FZU60. Bioresource Technology, 2019, 290: 121798.

(14) Ruijuan Ma, Xurui Zhao, Youping Xie*, Shih-Hsin Ho, Jianfeng Chen*. Enhancing lutein productivity of Chlamydomonas sp. via high-intensity light exposure with corresponding carotenogenic genes expression profiles. Bioresource Technology, 2019, 275: 416-420.

(15) Kongyong Lu^#, Xurui Zhao^#, Shih-Hsin Ho, Ruijuan Ma*, Youping Xie*, Jianfeng Chen. Biorefining and the functional properties of proteins from lipid and pigment extract residue of Chlorella pyrenoidosa. Marine Drugs, 2019, 17(8): 454.

(16) Youping Xie, Kongyong Lu, Xurui Zhao, Ruijuan Ma, Jianfeng Chen*, Shih-Hsin Ho*. Manipulating nutritional conditions and salinity-gradient stress for enhanced lutein production in marine microalga Chlamydomonas sp. Biotechnology Journal, 2019, 14: 1800380.

(17) Xurui Zhao, Ruijuan Ma, Xiaoting Liu, Shih-Hsin Ho, Youping Xie*, Jianfeng Chen*. Strategies related to light quality and temperature to improve lutein production of marine microalga Chlamydomonas sp. Bioprocess and Biosystems Engineering, 2019, 42: 435-443.

(18) Ying Shen, Sha Wang, Shih-Hsin Ho, Youping Xie*, Jianfeng Chen*. Enhancing lipid production in attached culture of a thermotolerant microalga Desmodesmus sp. F51 using light-related strategies. Biochemical Engineering Journal, 2018, 129: 119-128.

(19) Ying Shen, Huan Li, Wenzhe Zhu, Shih-Hsin Ho, Wenqiao Yuan, Jianfeng Chen, Youping Xie*. Microalgal-biochar immobilized complex: A novel efficient biosorbent for cadmium removal from aqueous solution. Bioresource Technology, 2017, 244: 1031-1038.

(20) Youping Xie, Xurui Zhao, Jianfeng Chen, Xuqiu Yang, Shih-Hsin Ho, Baobei Wang, Jo-Shu Chang, Ying Shen*. Enhancing cell growth and lutein productivity of Desmodesmus sp. F51 by optimal utilization of inorganic carbon sources and ammonium salt. Bioresource Technology, 2017, 244: 664-671.

(21) Youping Xie, Shih-Hsin Ho, Ching-Nen Nathan Chen, Chun-Yen Chen, Keju Jing, I-Son Ng, Jianfeng Chen, Jo-Shu Chang*, Yinghua Lu*. Disruption of thermo-tolerant Desmodesmus sp. F51 in high pressure homogenization as a prelude to carotenoids extraction. Biochemical Engineering Journal, 2016, 109: 243-251.

(22) Youping Xie, Yiwen Jin, Xianhai Zeng, Jianfeng Chen, Yinghua Lu, Keju Jing*. Fed-batch strategy for enhancing cell growth and C-phycocyanin production of Arthrospira (Spirulina) platensis under phototrophic cultivation. Bioresource Technology, 2015, 180: 281-287.

獲獎(jiǎng)情況：

2022年，beat365在線體育官網(wǎng)優(yōu)秀碩士學(xué)位論文指導(dǎo)教師

2021年，福建省級(jí)高層次人才C類

2020年，福建省優(yōu)秀碩士學(xué)位論文指導(dǎo)教師

2020年，beat365在線體育官網(wǎng)優(yōu)秀碩士學(xué)位論文指導(dǎo)教師

2019年，福建省優(yōu)秀碩士學(xué)位論文指導(dǎo)教師

2019年，beat365在線體育官網(wǎng)優(yōu)秀碩士學(xué)位論文指導(dǎo)教師

2018年，2017年度福建省科技進(jìn)步獎(jiǎng)三等獎(jiǎng)，福建省人民政府

2017年，Bioresource Technology期刊杰出審稿人，Elsevier

2017年，Algal Research期刊杰出審稿人，Elsevier

2016年，Biochemical Engineering Journal期刊杰出審稿人，Elsevier

個(gè)人網(wǎng)頁：https://www.researchgate.net/profile/Youping_Xie

https://webofscience.clarivate.cn/wos/author/record/AAD-3105-2020